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For research use only.

Verified Samples Verified Samples in WB: HT-29
Verified Samples in IF: HepG2
Dilution WB 1:1000,  IHC-P 1:1000-1:5000,  ICC/IF 1:50-1:100,  FCM 1:1:50-1:100
Isotype Rabbit IgG
Host Rabbit
Reactivity Human
Applications WB,  IHC-P,  ICC/IF,  FC
Clonality Monoclonal;Recombinant
Immunogen A synthetic peptide of human MUC13
Abbre MUC13
Synonyms Muc,  UNQ,  DRCC,  DRCC1,  RECC,  MUC13,  UNQ6194,  PRO20221,  Down-regulated in colon cancer 1
Swissprot
Calculated MW 55 kDa
Cellular Localization Cell membrane and Secreted
Concentration 1 mg/mL
Buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Purification Method Protein A purified
Research Areas Signal Transduction,  Cancer
Clone C311391
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Ice bag
background Mucin 13 (MUC13) is a high-molecular-weight transmembrane glycoprotein that is frequently and aberrantly expressed in a variety of epithelial carcinomas, including gastric, colorectal, and ovarian cancers. On the basis of the high expression of MUC13 in cancer cells as well as recent laboratory findings suggesting a malignant phenotype of MUC13-transfected cell lines, the oncogenic potential of MUC13 has emerged. The various functional domains of MUC13 may confer oncogenic potential to MUC13. MUC13 exhibits the characteristics suitable as an early marker for cancer screening and presents a promising target for antibody-guided targeted therapy.
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