Recombinant Rat CD73/NT5E Protein (His Tag)
Price: $ 447
Price: $ 257
Size:
50μg
10μg
Quantity:
- Expression Host: HEK293 Cells
- Accession: P21588
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Product Details
Synonyms | CD73;E5NT;Nucleotidase;NT5E;ecto-5'-nucleotidase;5'-Nucleotidase |
Species | Rat |
Expression Host | HEK293 Cells |
Sequence | Trp29-Lys549 |
Accession | P21588 |
Calculated Molecular Weight | 59.0 kDa |
Observed Molecular Weight | 70-90 kDa |
Tag | C-His |
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 120mM NaCl, 4mM CaCl2, 20% Glycerol, pH 7.5. |
Reconstitution | Not Applicable |
Background | CD73, also known as Ecto-5'-nucleotidase, is an ectoenzyme that is attached to the cell membrane by a glycosyl phophatidylinositol anchor. The enzyme is expressed by most cell types. The 5 ’ -Nucleotidase activity of CD73 converts extracellular nucleoside-5 ’ -monophosphates to nucleosides. CD73 is one of several enzymes responsible for the production of extracellular adenosine, a signaling molecule that is involved in responses to inflammation and tissue injury. CD73 hydrolyzes extracellular nucleotides into membrane permeable nucleosides. |