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Recombinant Rhesus macaque IFNAR1 Protein (His Tag)

Cat:PKSQ050073
Manual MSDS

Price: $ 375

Price: $ 129

Size:
50μg 10μg
Quantity:
  • Expression Host: HEK293 Cells
  • Accession: XP_005548864.1
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Product Details
Synonyms Alpha-type antiviral protein;AVP;beta-type antiviral protein;CRF2-1;Cytokine receptor class-II member 1;Cytokine receptor family 2 member 1;human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC;IFN-alpha/beta R1;IFN-alpha/beta receptor 1;IFN-alpha-REC;IFNAR;IFNAR1;IFN-aR1;IFNBR;IFNbR1;IFN-bR1;IFN-R-1
Species Rhesus macaque
Expression Host HEK293 Cells
Sequence Ala25-Lys437
Accession XP_005548864.1
Calculated Molecular Weight 48.4 kDa
Observed Molecular Weight 70-120 kDa
Tag C-His
Purity > 95 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.
Background Interferon?alpha/beta receptor 1 (IFN? alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphorylation at Tyr-466. It also interacts with FBXW11, the substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.