REN Polyclonal Antibody

Uniprot : P00797
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14668

      Synonyms:Angiotensin forming enzyme,Angiotensin forming enzyme precursor,Angiotensinogenase,Angiotensinogenase precursor,FLJ10761,HNFJ2,REN,Ren1,RENI,Renin,Renin precursor renal

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Angiotensin forming enzyme,Angiotensin forming enzyme precursor,Angiotensinogenase,Angiotensinogenase precursor,FLJ10761,HNFJ2,REN,Ren1,RENI,Renin,Renin precursor renal
      Swissprot P00797
      Source Rabbit
      Reactivity Human
      Immunogen Recombinant protein of human REN
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Secreted. Membrane. Associated to membranes via binding to ATP6AP2.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined.

      Images

      Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using REN Polyclonal Antibody at dilution 1:40

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using REN Polyclonal Antibody at dilution 1:40

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