RETNLB Polyclonal Antibody (E-AB-10579)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human colon cancer, Human cervical cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human RETNLB |
| Abbre | RETNLB |
| Synonyms | C/EBP epsilon regulated myeloid specific secreted cysteine rich protein precursor 2, CCGR, Colon and small intestine specific cysteine rich protein, Colon and small intestine-specific cysteine-rich protein, Colon carcinoma, Colon carcinoma related gene protein |
| Swissprot | |
| Cellular Localization | Secreted. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Resistin-like betais aproteinthat in humans is encoded by theRETNLBgene. An infusion of either resistin or RELMB in rats rapidly induced severe hepatic but not peripheral insulin resistance. Increases in circulating resistin or RELMB levels markedly stimulated hepatic glucose production despite the presence of fixed physiologic insulin levels. This enhanced rate of glucose output was due to increased flux through glucose-6-phosphatase. The results supported the notion that a novel family of fat- and gut-derived circulating proteins modulates hepatic insulin action. |
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