RRAD Polyclonal Antibody (E-AB-16047)
For research use only.
Verified Samples |
Verified Samples in IHC: Human brain, Human colon cancer |
Dilution | IHC 1:50-1:200 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human RRAD |
Abbre | RRAD |
Synonyms | GTP binding protein RAD, GTP-binding protein RAD, RAD, RAD1, RAS (RAD and GEM) like GTP binding 3, REM3, RRAD, Ras associated with diabetes, Ras related associated with diabetes |
Swissprot | |
Cellular Localization | Cell membrane. |
Concentration | 0.2 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cardiovascular, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein may be important in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca2+ currents. As regulator of voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway and phosphorylation and activation of CAMK2D. Mostly expressed in the heart and muscle of type II diabetic humans. Also found in the skeletal muscle, lung and adipose tissue. Lesser amounts in placenta and kidney. |
Other Clones
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Other Formats
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Unconjugated
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