RTN4 Polyclonal Antibody (E-AB-16006)
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For research use only.
| Verified Samples |
Verified Samples in WB: RAW264.7 Verified Samples in IHC: Human lung cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human RTN4 |
| Abbre | RTN4 |
| Synonyms | NSP, Nogo, Nogo A, Nogo B, RTN x, RTN4, RTN4A, RTNX, Reticulon 4, Reticulon 5 |
| Swissprot | |
| Calculated MW | 40 kDa |
| Cellular Localization | Endoplasmic reticulum, endoplasmic reticulum membrane, multi-pass membrane protein, Note=Anchored to the membrane of the endoplasmic reticulum through 2 putative transmembrane domains. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified. |
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