SEPT7 Polyclonal Antibody

Uniprot : Q16181
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-11062

      Synonyms:CDC10,CDC10 protein homolog,CDC3,Cell division cycle 10,NBLA02942,SEPT7,SEPT7,SEPT7A,Septin 7,Septin-7

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CDC10,CDC10 protein homolog,CDC3,Cell division cycle 10,NBLA02942,SEPT7,SEPT7,SEPT7A,Septin 7,Septin-7
      Swissprot Q16181
      Source Rabbit
      Reactivity Human ,Mouse ,Rat
      Immunogen Recombinant protein of human SEPT7
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R217),ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300
      Concentration 0.5 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Chromosome>centromere>kinetochore. Cytoplasm>cytoskeleton>spindle. Cleavage furrow. Midbody. Cytoplasm>cytoskeleton>cilium axoneme. Distributed throughout the cytoplasm in prometaphase cells. Associated with the spindle during metaphase. Associated with the central spindle and at the cleavage furrow in anaphase cells. Detected at the midbody in telophase. Associated with actin stress fibers.
      Tissue specificity Widely expressed.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19

      Images

      polyclonal antibody-Elabscience

      Western Blot analysis of Hela cell using SEPT7 Polyclonal Antibody at dilution of 1:380

      polyclonal antibody-Elabscience

      Immunohistochemistry of paraffin-embedded Human colon cancer using SEPT7 Polyclonal Antibody at dilution of 1:50

      polyclonal antibody-Elabscience

      Immunohistochemistry of paraffin-embedded Human gastric cancer using SEPT7 Polyclonal Antibody at dilution of 1:50

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