SERPINB5 Polyclonal Antibody

Uniprot : P36952
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14208

      Synonyms:Maspin,Ovalbumin,Peptidase inhibitor 5,PI-5,PI5,protease inhibitor 5 (maspin),Protease inhibitor 5,Serine (or cysteine) peptidase inhibitor,clade B,member 5,serine (or cysteine) proteinase inhibitor,clade B (ovalbumin),member 5,Serpin B5,serpin family B member 5,Serpin peptidase inhibitor,Serpin peptidase inhibitor,clade B (ovalbumin),member 5,Serpinb5,SPB5,Spi5,Spi7

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Maspin,Ovalbumin,Peptidase inhibitor 5,PI-5,PI5,protease inhibitor 5 (maspin),Protease inhibitor 5,Serine (or cysteine) peptidase inhibitor,clade B,member 5,serine (or cysteine) proteinase inhibitor,clade B (ovalbumin),member 5,Serpin B5,serpin family B member 5,Serpin peptidase inhibitor,Serpin peptidase inhibitor,clade B (ovalbumin),member 5,Serpinb5,SPB5,Spi5,Spi7
      Swissprot P36952
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human SERPINB5
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300
      Concentration 0.5 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Secreted>extracellular space.
      Tissue specificity Normal mammary epithelial cells.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background Maspin (mammary serine protease inhibitor) also known as serpin B5 is a protein that in humans is encoded by the SERPINB5 gene.[1] This protein belongs to the serpin (serine protease inhibitor) superfamily.[1] SERPINB5 also functions as a tumor suppressor gene in epithelial cells. The expressed protein suppresses the ability of cancer cells to invade and metastasize other tissues. The protein also functions as an angiogenesis inhibitor.It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

      Images

      Western Blot analysis of Mouse lung tissue using SERPINB5 Polyclonal Antibody at dilution of 1:1000

      Immunohistochemistry of paraffin-embedded Human esophagus cancer using SERPINB5 Polyclonal Antibody at dilution of 1:60

      Immunohistochemistry of paraffin-embedded Human ovarian cancer using SERPINB5 Polyclonal Antibody at dilution of 1:60

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