SETD2 Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human;Mouse
- Applications: IHC
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Product Details
Verified Samples |
Verified Samples in IHC:Human tonsil,Human cervical cancer |
Dilution |
IHC 1:50-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human SETD2 |
Abbre | SETD2 |
Synonyms | EC 2.1.1.43;FLJ16420;FLJ22472;FLJ23184;FLJ45883;HBP231;HIF 1;HIF-1;HIF1;HIP-1;Histone lysine N methyltransferase SETD2;Histone-lysine N-methyltransferase SETD2;hSET2;HSPC069;Huntingtin interacting protein 1;Huntingtin interacting protein;Huntingtin interacting protein B;Huntingtin interacting protein HYPB;Huntingtin yeast partner B;Huntingtin-binding protein;231-KD;Huntingtin-interacting protein 1;Huntingtin-interacting protein B;HYPB;KIAA1732;KMT3A;Lysine N methyltransferase 3A;Lysine N-methyltransferase 3A;p231HBP;SET domain containing 2;SET domain-containing protein 2;SET2;SETD2;SETD2 |
Swissprot | |
Cellular Localization | Nucleus. Chromosome. |
Concentration | 0.2 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol