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SETD2 Polyclonal Antibody

Cat:E-AB-10851
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse
  • Applications: IHC
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Product Details
Verified Samples Verified Samples in IHC:Human tonsil,Human cervical cancer
Dilution

IHC 1:50-1:200

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant protein of human SETD2
Abbre SETD2
Synonyms EC 2.1.1.43;FLJ16420;FLJ22472;FLJ23184;FLJ45883;HBP231;HIF 1;HIF-1;HIF1;HIP-1;Histone lysine N methyltransferase SETD2;Histone-lysine N-methyltransferase SETD2;hSET2;HSPC069;Huntingtin interacting protein 1;Huntingtin interacting protein;Huntingtin interacting protein B;Huntingtin interacting protein HYPB;Huntingtin yeast partner B;Huntingtin-binding protein;231-KD;Huntingtin-interacting protein 1;Huntingtin-interacting protein B;HYPB;KIAA1732;KMT3A;Lysine N methyltransferase 3A;Lysine N-methyltransferase 3A;p231HBP;SET domain containing 2;SET domain-containing protein 2;SET2;SETD2;SETD2
Swissprot
Cellular Localization Nucleus. Chromosome.
Concentration 0.2 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.