SETD2 Polyclonal Antibody (E-AB-10851)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human tonsil, Human cervical cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human SETD2 |
| Abbre | SETD2 |
| Synonyms | 231-KD, EC 2.1.1.43, FLJ16420, FLJ22472, FLJ23184, FLJ45883, HBP231, HIF 1, HIF-1, HIF1, HIP-1, Histone lysine N methyltransferase SETD2, Histone-lysine N-methyltransferase SETD2, hSET2, HSPC069, Huntingtin intera, Huntingtin interacting protein, Huntingtin interacting protein 1, Huntingtin interacting protein B, Huntingtin interacting protein HYPB, Huntingtin yeast partner B, Huntingtin-binding protein, Huntingtin-interacting protein 1, Huntingtin-interacting protein B, HYPB, KIAA1732, KMT3A, Lysine N methyltransferase 3A, Lysine N-methyltransferase 3A, p231HBP, SET domain containing 2, SET domain-containing protein 2, SET2, SETD2, SETD2抗体 |
| Swissprot | |
| Cellular Localization | Nucleus. Chromosome. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. |
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