SIGMAR1 Polyclonal Antibody

Uniprot : Q99720
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14664

      Synonyms:Aging associated gene 8 protein,Aging-associated gene 8 protein,AL024364,hSigmaR1,mSigmaR1,opioid receptor,sigma 1,opioid receptor,sigma 1 isoform 1,RP23 167I12.6,SGMR1,SIG 1R,SIG-1R,Sigma 1-type opioid receptor,Sigma non-opioid intracellular receptor 1,sigma1 receptor,Sigma1-receptor,Sigma1R,Sigmar1,SR BP,SR-BP,SR31747 binding protein,SR31747-binding protein,SRBP

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Aging associated gene 8 protein,Aging-associated gene 8 protein,AL024364,hSigmaR1,mSigmaR1,opioid receptor,sigma 1,opioid receptor,sigma 1 isoform 1,RP23 167I12.6,SGMR1,SIG 1R,SIG-1R,Sigma 1-type opioid receptor,Sigma non-opioid intracellular receptor 1,sigma1 receptor,Sigma1-receptor,Sigma1R,Sigmar1,SR BP,SR-BP,SR31747 binding protein,SR31747-binding protein,SRBP
      Swissprot Q99720
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human SIGMAR1
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300
      Concentration 0.4 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus inner membrane. Nucleus outer membrane. Endoplasmic reticulum membrane. Lipid droplet. Cell junction. Cell membrane. Cell projection>growth cone. Targeted to lipid droplets, cholesterol and galactosylceramide-enriched domains of the endoplasmic reticulum. Enriched at cell-cell communication regions, growth cone and postsynaptic structures. Localization is modulated by ligand-binding.
      Tissue specificity Widely expressed with higher expression in liver, colon, prostate, placenta, small intestine, heart and pancreas. Expressed in the retina by retinal pigment epithelial cells.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.

      Images

      Western Blot analysis of Mouse liver and brain tissue, A549 cell using SIGMAR1 Polyclonal Antibody at dilution of 1:310

      Immunohistochemistry of paraffin-embedded Human gastic cancer using SIGMAR1 Polyclonal Antibody at dilution of 1:50

      Immunohistochemistry of paraffin-embedded Human liver cancer using SIGMAR1 Polyclonal Antibody at dilution of 1:50

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