SLC7A11 Polyclonal Antibody

Uniprot : Q9UPY5
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-17625

      Synonyms:Amino acid transport system xc xCT,Amino acid transport system xc-,Calcium channel blocker resistance protein CCBR1,Calcium channel blocker resistance protein CCBR1,CCBR1,Cysteine/glutamate transporter,Cystine/glutamate transporter,OTTHUMP00000164578,SLC7A11,Solute carrier family 7 (anionic amino acid transporter light chain,xc- system),member 11,solute carrier family 7,Solute carrier family 7 member 11,Solute carrier family 7,(cationic amino acid transporter,y+ system) member 11,SYSTEM Xc(-) TRANSPORTER-RELATED PROTEIN,xCT,XCT

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Amino acid transport system xc xCT,Amino acid transport system xc-,Calcium channel blocker resistance protein CCBR1,Calcium channel blocker resistance protein CCBR1,CCBR1,Cysteine/glutamate transporter,Cystine/glutamate transporter,OTTHUMP00000164578,SLC7A11,Solute carrier family 7 (anionic amino acid transporter light chain,xc- system),member 11,solute carrier family 7,Solute carrier family 7 member 11,Solute carrier family 7,(cationic amino acid transporter,y+ system) member 11,SYSTEM Xc(-) TRANSPORTER-RELATED PROTEIN,xCT,XCT
      Swissprot Q9UPY5
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Synthetic peptide of human SLC7A11
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:20-100, ELISA 1:2000-5000
      Concentration 0.4mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Membrane.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.

      Images

      Immunohistochemistry of paraffin-embedded Human brain using SLC7A11 Polyclonal Antibody at dilution of 1/35

      Immunohistochemistry of paraffin-embedded Human thyroid cancer using SLC7A11 Polyclonal Antibody at dilution of 1/35

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