SNAI1 Polyclonal Antibody

Uniprot : O95863
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-32931

      Synonyms:dJ710H13.1,Protein sna,Protein snail homolog 1,Protein snail homolog,SLUGH2,SNA,Sna protein,SNAH,SNAI,snai1,SNAI1,Snail 1 homolog,Snail 1 zinc finger protein,SNAIL,Snail family transcriptional repressor 1,Snail homolog 1 (Drosophila),SNAIL,Drosophila,homolog of,1,SNAIL1,Zinc finger protein SNAI1

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,Mk

      Applications: WB,IHC-p,IF,ELISA

      Lead Time: 2 daysWelcome to order from local distributors.

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      Overview

      Synonyms dJ710H13.1,Protein sna,Protein snail homolog 1,Protein snail homolog,SLUGH2,SNA,Sna protein,SNAH,SNAI,snai1,SNAI1,Snail 1 homolog,Snail 1 zinc finger protein,SNAIL,Snail family transcriptional repressor 1,Snail homolog 1 (Drosophila),SNAIL,Drosophila,homolog of,1,SNAIL1,Zinc finger protein SNAI1
      Swissprot O95863
      Source Rabbit
      Reactivity Human,Mouse,Monkey
      Immunogen Synthesized peptide derived from human SNAI 1 around the non-phosphorylation site of Ser246.
      Application WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),IF,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus. Cytoplasm. Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs.
      Tissue specificity Expressed in a variety of tissues with the highest expression in kidney. Expressed in mesenchymal and epithelial cell lines.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.

      Images

      Western Blot analysis of 3T3 cells using SNAI1 Polyclonal Antibody at dilution of 1:1000.

      Immunofluorescence analysis of Rat spleen tissue using SNAI1 Polyclonal Antibody at dilution of 1:200.

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