SNCA Polyclonal Antibody

Uniprot : P37840
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-36111

      Synonyms:Alpha synuclein,Alpha-synuclein,Alpha-synuclein,isoform NACP140,alphaSYN,MGC105443,MGC110988,MGC127560,MGC64356,NACP,Non A beta component of AD amyloid,Non A4 component of amyloid,Non A4 component of amyloid precursor,Non-A beta component of AD amyloid,Non-A-beta component of alzheimers disease amyloid,precursor of,Non-A4 component of amyloid precursor,Non-A4 component of amyloid,precursor of,OTTHUMP00000218549,OTTHUMP00000218551,OTTHUMP00000218552,OTTHUMP00000218553,OTTHUMP00000218554,PARK 1,PARK 4,PARK1,PARK4,Parkinson disease (autosomal dominant,Lewy body) 4,Parkinson disease familial 1,SNCA,Snca synuclein,alpha (non A4 component of amyloid precursor),SYN,Synuclein alpha,Synuclein alpha 140,Synuclein,alpha (non A4 component of amyloid precursor),SYUA

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC-p,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Alpha synuclein,Alpha-synuclein,Alpha-synuclein,isoform NACP140,alphaSYN,MGC105443,MGC110988,MGC127560,MGC64356,NACP,Non A beta component of AD amyloid,Non A4 component of amyloid,Non A4 component of amyloid precursor,Non-A beta component of AD amyloid,Non-A-beta component of alzheimers disease amyloid,precursor of,Non-A4 component of amyloid precursor,Non-A4 component of amyloid,precursor of,OTTHUMP00000218549,OTTHUMP00000218551,OTTHUMP00000218552,OTTHUMP00000218553,OTTHUMP00000218554,PARK 1,PARK 4,PARK1,PARK4,Parkinson disease (autosomal dominant,Lewy body) 4,Parkinson disease familial 1,SNCA,Snca synuclein,alpha (non A4 component of amyloid precursor),SYN,Synuclein alpha,Synuclein alpha 140,Synuclein,alpha (non A4 component of amyloid precursor),SYUA
      Swissprot P37840
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthesized peptide derived from the Internal region of human Synuclein-α.
      Application WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R217),ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300 ELISA 1:10000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm, cytosol. Membrane. Nucleus. Cell junction, synapse. Secreted. Membrane-bound in dopaminergic neurons.
      Tissue specificity Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene.

      Images

      polyclonal antibody-Elabscience

      Western Blot analysis of Hela cells using SNCA Polyclonal Antibody.

      polyclonal antibody-Elabscience

      Immunohistochemistry of paraffin-embedded Human kidney cancer tissue using SNCA Polyclonal Antibody at dilution of 1:200.

      polyclonal antibody-Elabscience

      Immunohistochemistry of paraffin-embedded Mouse brain tissue using SNCA Polyclonal Antibody at dilution of 1:200.

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      MSDS for ELISA ISO 9001

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