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SPDEF Polyclonal Antibody

Cat:E-AB-10535
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse
  • Applications: IHC
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Product Details
Verified Samples Verified Samples in IHC:Human colon cancer,Human tonsil
Dilution

IHC 1:50-1:200

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant protein of human SPDEF
Abbre SPDEF
Synonyms bA375E1.3;PDEF;Prostate derived Ets factor;PROSTATE EPITHELIUM SPECIFIC ETS TRANSCRIPTION FACTOR;Prostate epithelium-specific Ets transcription factor;Prostate specific Ets;Prostate-derived Ets factor;Prostate-specific Ets;PSE;RP11-375E1__A.3;SAM POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR;SAM pointed domain-containing Ets transcription factor;Spdef;SPDEF
Swissprot
Cellular Localization Nucleus.
Concentration 1 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.