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SPTA1 Polyclonal Antibody

Cat:E-AB-63689
Manual MSDS
  • +3

Price: $ 530

Price: $ 320

Price: $ 200

Size:
200μL 120μL 60μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse;Rat
  • Applications: IHC;IF
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For research use only. Order now, ship in 3 days

Product Details
Verified Samples Verified Samples in IHC:Human tonsil,Rat spleen,Mouse liver
Verified Samples in IF:Rat bone marrow,Mouse lung
Dilution

IHC 1:50-1:200, IF 1:50-1:200

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant fusion protein of human SPTA1 (NP_003117.2).
Abbre SPTA1
Synonyms SPTA1;EL2;HPP;HS3;SPH3;SPTA
Swissprot
Cellular Localization Cytoplasm > cytoskeleton. Cytoplasm > cell cortex.
Concentration 1mg/mL
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method Affinity purification
Research Areas Cancer; Cardiovascular; Signal transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Ice bag
background Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.