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STAT6 Polyclonal Antibody

Cat:E-AB-10059
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse
  • Applications: WB
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Product Details
Verified Samples Verified Samples in WB:Raji
Dilution

WB 1:500-1:2000

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Recombinant protein of human STAT6
Abbre STAT6
Synonyms 12S1644;D12S1644;IL 4 STAT;IL-4 Stat;IL4 STAT;Interleukin 4 Induced;Interleukin 4 Induced Transcription Factor IL4 STAT;Signal transducer and activator of transcription 6;Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced;Signal Transducer And Activator Of Transcription 6 Nirs Variant 1;Signal transducer and activator of transcription 6;interleukin 4 induced;STAT 6;STAT interleukin4 induced;STAT;interleukin4 induced;Stat6;STAT6;STAT6B;STAT6C;Transcription factor IL 4 STAT
Swissprot
Calculated MW 94kDa
Cellular Localization Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.
Concentration 0.2 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Epigenetics and Nuclear Signaling; Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.