STK40 Polyclonal Antibody

Uniprot : Q8N2I9
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14693

      Synonyms:2310004N11Rik,MGC4796,OTTHUMP00000009948,OTTHUMP00000009951,RP11-268J15.4,Ser/Thr like kinase,Serine/threonine kinase 40,Serine/threonine protein kinase 40,SgK495,SHIK,SINK homologous serine/threonine protein kinase,SINK-homologous inhibitory kinase,STK 40,Sugen kinase 495

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms 2310004N11Rik,MGC4796,OTTHUMP00000009948,OTTHUMP00000009951,RP11-268J15.4,Ser/Thr like kinase,Serine/threonine kinase 40,Serine/threonine protein kinase 40,SgK495,SHIK,SINK homologous serine/threonine protein kinase,SINK-homologous inhibitory kinase,STK 40,Sugen kinase 495
      Swissprot Q8N2I9
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human STK40
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasmic and Nuclear
      Tissue specificity Strongly expressed in heart, brain, placenta, lung, skeletal muscle, kidney, spleen, thymus, prostate, liver, pancreas, testis, ovary, small intestine, colon and peripheral blood leukocytes.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background STK40 (Serine/threonine-protein kinase 40), also known as Sugen kinase 495, is a 435 amino acid protein kinase that may be a negative regulator of NFκB and p53-mediated gene expression. Localized to both the cytoplasm and the nucleus, STK40 is ubiquitously expressed. STK40 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regulates activation of MAP kinases and inhibits NFκB-mediated gene transcription. Similarly, overexpression of STK40 inhibits NFκB activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK40 that are produced as a result of alternative splicing.

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using STK40 Polyclonal Antibody at dilution 1:40

      Immunohistochemistry of paraffin-embedded Human lung cancer tissue using STK40 Polyclonal Antibody at dilution 1:40

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