STRADB Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human;Mouse
- Applications: WB
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Product Details
Verified Samples |
Verified Samples in WB:Mouse pancreas |
Dilution |
WB 1:200-1:1000 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human STRADB |
Abbre | STRADB |
Synonyms | ALS2 chromosome region gene 2;ALS2CR2;Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 2;Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein;CALS 21;CALS-21;ILP interacting protein ILPIPA;ILP-interacting protein;ILPIP;ILPIPA;Likely ortholog of mouse polyploidy associated protein kinase;PAPK;PRO1038;Pseudokinase ALS2CR2;STE20-related kinase adapter protein beta;STRAB;STRAD beta;STRADB |
Swissprot | |
Calculated MW | 47/31kDa |
Cellular Localization | Nucleus. Cytoplasm. |
Concentration | 0.1 mg/mL |
Buffer | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method | Affinity purification |
Research Areas | Cancer; Metabolism; Neuroscience |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol