STX1A Polyclonal Antibody (E-AB-16084)
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For research use only.
| Verified Samples |
Verified Samples in WB: Mouse brain Verified Samples in IHC: Human ovarian cancer |
| Dilution | WB 1:1000-1:5000, IHC 1:50-1:200 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human STX1A |
| Abbre | STX1A |
| Synonyms | HPC 1, Neuron specific antigen HPC1, Neuron-specific antigen HPC-1, OTTHUMP00000174615, OTTHUMP00000174616, OTTHUMP00000174617, OTTHUMP00000174618, P35-1, STX1, STX1A, SYN1A, Syntaxin 1A (brain), Syntaxin 1A brain, Syntaxin-1A |
| Swissprot | |
| Calculated MW | 33 kDa |
| Cellular Localization | Secreted and Cytoplasmic vesicle>secretory vesicle>synaptic vesicle membrane. Cell junction>synapse>synaptosome. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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