Tau Monoclonal Antibody

Uniprot : P10636
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
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    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience

      Catalog number:E-AB-22141

      Synonyms:AI413597,AW045860,DDPAC,FLJ31424,FTDP 17,G protein beta1/gamma2 subunit interacting factor 1,MAPT,MAPTL,MGC134287,MGC138549,MGC156663,Microtubule associated protein tau,Microtubule associated protein tau isoform 4,Microtubule-associated protein tau,MSTD,Mtapt,MTBT1,MTBT2,Neurofibrillary tangle protein,Paired helical filament tau,Paired helical filament-tau,PHF tau,PHF-tau,PPND,PPP1R103,Protein phosphatase 1,regulatory subunit 103,pTau,RNPTAU,TAU,TAU,Tauopathy and respiratory failure,included

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Mouse

      Reactivity: H,M,R

      Applications: WB,IHC-p

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms AI413597,AW045860,DDPAC,FLJ31424,FTDP 17,G protein beta1/gamma2 subunit interacting factor 1,MAPT,MAPTL,MGC134287,MGC138549,MGC156663,Microtubule associated protein tau,Microtubule associated protein tau isoform 4,Microtubule-associated protein tau,MSTD,Mtapt,MTBT1,MTBT2,Neurofibrillary tangle protein,Paired helical filament tau,Paired helical filament-tau,PHF tau,PHF-tau,PPND,PPP1R103,Protein phosphatase 1,regulatory subunit 103,pTau,RNPTAU,TAU,TAU,Tauopathy and respiratory failure,included
      Swissprot P10636
      Source Mouse
      Reactivity Human,Mouse,Rat
      Immunogen Synthetic Peptide of Tau
      Application WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R217)
      Recommended dilution WB 1:1000-2000, IHC 1:100-200
      Concentration 1 mg/mL
      Clonality Monoclonal

      Properties

      Cellular localization Cytoplasm>cytosol. Cell membrane. Cytoplasm>cytoskeleton. Cell projection>axon. Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components.
      Tissue specificity Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
      Clone No. Clone:8A3
      Isotype IgG
      Purification Protein A purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

      Images

      monoclonal antibody-Elabscience

      Western Blot analysis of various cells using Tau Polyclonal Antibody at dilution of 1:1000.

      monoclonal antibody-Elabscience

      Immunohistochemistry of paraffin-embedded Rat brain tissue using Tau Polyclonal Antibody at dilution of 1:200.

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