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TBP Monoclonal Antibody

Cat:E-AB-22171
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Mouse
  • Reactivity: Human;Mouse;Rat
  • Applications: IHC-p
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Product Details
Verified Samples Verified Samples in IHC:Human breast carcinoma,Mouse kidney
Dilution

IHC 1:50-200

Western Blot Operation Guide
Clonality Monoclonal
Immunogen Recombinant Protein
Abbre TBP/TATA Binding Protein
Synonyms GTF2D;GTF2D1;HDL4;SCA17;TATA binding factor;TATA box binding protein;TATA box factor;TATA sequence binding protein;TATA sequence-binding protein;TATA-binding factor;TATA-box factor;TATA-box-binding protein;TBP;TBP;TFIID;Transcription initiation factor TFIID TBP subunit
Swissprot
Cellular Localization Nucleus.
Tissue Specificity Widely expressed, with levels highest in the testis and ovary.
Concentration 1 mg/mL
Buffer PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method Protein A purification
Research Areas Cancer; Epigenetics and Nuclear Signaling
Clone No. 1F6
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.