TBP Monoclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Mouse
- Reactivity: Human;Mouse;Rat
- Applications: IHC-p
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Product Details
Verified Samples |
Verified Samples in IHC:Human breast carcinoma,Mouse kidney |
Dilution |
IHC 1:50-200 Western Blot Operation Guide |
Clonality | Monoclonal |
Immunogen | Recombinant Protein |
Abbre | TBP/TATA Binding Protein |
Synonyms | GTF2D;GTF2D1;HDL4;SCA17;TATA binding factor;TATA box binding protein;TATA box factor;TATA sequence binding protein;TATA sequence-binding protein;TATA-binding factor;TATA-box factor;TATA-box-binding protein;TBP;TBP;TFIID;Transcription initiation factor TFIID TBP subunit |
Swissprot | |
Cellular Localization | Nucleus. |
Tissue Specificity | Widely expressed, with levels highest in the testis and ovary. |
Concentration | 1 mg/mL |
Buffer | PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4 |
Purification Method | Protein A purification |
Research Areas | Cancer; Epigenetics and Nuclear Signaling |
Clone No. | 1F6 |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Biological ice pack at 4 ℃ |
background | This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol