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For research use only.

Verified Samples Verified Samples in IHC: Rat ovary, Human lung cancer, Human liver cancer, Human placenta
Dilution IHC 1:50-1:200
Isotype Rabbit IgG
Host Rabbit
Reactivity Human,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Recombinant fusion protein of human TES (NP_056456.1).
Abbre TES
Synonyms TES,  TESS,  TESS-2,  testin,  testin抗体
Swissprot
Cellular Localization Cell junction, Cytoplasm.
Concentration 1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Epigenetics and Nuclear Signaling,  Signal Transduction,  Cancer
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.
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