THOC7 Polyclonal Antibody (E-AB-10940)
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For research use only.
| Verified Samples |
Verified Samples in WB: Mouse spleen, Human fetal liver, Hela, Mouse testis, A431 Verified Samples in IHC: Human lung cancer |
| Dilution | WB 1:500-1:2000, IHC 1:25-1:100 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human THOC7 |
| Abbre | THOC7 |
| Synonyms | FLJ23445, Functional spliceosome associated protein 24, Functional spliceosome-associated protein 24, Ngg1 interacting factor 3 like 1 binding protein 1, Ngg1 interacting factor 3 like protein 1 binding protein 1, Ngg1-interacting factor 3-like , fSAP24, hTREX30 |
| Swissprot | |
| Calculated MW | 24 kDa |
| Cellular Localization | Cytoplasm. Nucleus. Interaction with THOC5 is required for nuclear localization. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | NIF3L1 BP1 (Ngg1-interacting factor 3-like 1 binding protein 1), also known as THOC7 (THO complex subunit 7 homolog), fSAP24 or hTREX30, is a 204 amino acid cytoplasmic and nuclear protein that belongs to the THOC7 family and interacts with NIF3L1.NIF3L1 BP1 is a component of the THO/TREX complex that is recruited to transcribed genes and travels along with RNA polymerase II (Pol II) during elongation, coupling Pol II with RNA splicing and export factors.The THO/TREX complex also plays a role in the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.The gene that encodes NIF3L1 BP1 maps to human chromosome 3p14.1. |
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