TLR5 Polyclonal Antibody

Uniprot : O60602
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14647

      Synonyms:FLJ10052,MGC126430,MGC126431,SLEB1,TIL 3,TIL3,TLR 5,Tlr5,TLR5,Toll like receptor 5,Toll like receptor 5 precursor,Toll-like receptor 5,Toll/interleukin 1 receptor like protein 3,Toll/interleukin-1 receptor-like protein 3

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms FLJ10052,MGC126430,MGC126431,SLEB1,TIL 3,TIL3,TLR 5,Tlr5,TLR5,Toll like receptor 5,Toll like receptor 5 precursor,Toll-like receptor 5,Toll/interleukin 1 receptor like protein 3,Toll/interleukin-1 receptor-like protein 3
      Swissprot O60602
      Source Rabbit
      Reactivity Human
      Immunogen Recombinant protein of human TLR5
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:50-1:200
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Membrane.
      Tissue specificity Highly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using TLR5 Polyclonal Antibody at dilution 1:30

      Immunohistochemistry of paraffin-embedded Human liver cancer tissue using TLR5 Polyclonal Antibody at dilution 1:30

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