TP53BP2 Polyclonal Antibody

Uniprot : Q13625
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14774

      Synonyms:53BP2,Apoptosis stimulating of p53 protein 2,Apoptosis stimulating protein of p53 2,Apoptosis-stimulating of p53 protein 2,ASPP2,ASPP2,BBP,Bcl2 binding protein,Bcl2-binding protein,NY REN 51 antigen,p53 binding protein 2,p53-binding protein 2,p53BP2,PPP1R13A,Renal carcinoma antigen NY-REN-51,Tp53bp2,Tumor protein p53 binding protein 2,Tumor suppressor p53 binding protein 2,Tumor suppressor p53-binding protein 2

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms 53BP2,Apoptosis stimulating of p53 protein 2,Apoptosis stimulating protein of p53 2,Apoptosis-stimulating of p53 protein 2,ASPP2,ASPP2,BBP,Bcl2 binding protein,Bcl2-binding protein,NY REN 51 antigen,p53 binding protein 2,p53-binding protein 2,p53BP2,PPP1R13A,Renal carcinoma antigen NY-REN-51,Tp53bp2,Tumor protein p53 binding protein 2,Tumor suppressor p53 binding protein 2,Tumor suppressor p53-binding protein 2
      Swissprot Q13625
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human TP53BP2
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:50-1:200
      Concentration 0.5 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm>perinuclear region. Nucleus. Predominantly found in the perinuclear region. Some small fraction is nuclear. Sequester in the cytoplasm on overexpression of DDX42.
      Tissue specificity Widely expressed. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocyte. Reduced expression in breast carcinomas expressing a wild-type TP53 protein. Overexpressed in lung cancer cell lines.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.

      Images

      Western Blot analysis of Mouse kidney tissue, 293T and 231 cell using TP53BP2 Polyclonal Antibody at dilution of 1:375

      Immunohistochemistry of paraffin-embedded Human thyroid cancer using TP53BP2 Polyclonal Antibody at dilution of 1:35

      Immunohistochemistry of paraffin-embedded Human brain using TP53BP2 Polyclonal Antibody at dilution of 1:35

      • Show all (0)
      • Reviews (0)
      • Q&A (0)
      ... Show All Show Less
      MSDS for ELISA

      Browsing History


        People Also Bought