WEE1 Polyclonal Antibody (E-AB-19363)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human gastric cancer, Human prostate cancer |
| Dilution | IHC 1:30-1:150 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human WEE1 |
| Abbre | WEE1 |
| Synonyms | DKFZp686I18166, EC 2.7.10.2, FLJ16446, MGC105683, OTTHUMP00000231338, OTTHUMP00000231339, WEE 1 homolog 1 (S. pombe), WEE1, WEE1 homolog (S. pombe), WEE1 homolog S. pombe, Wee 1, Wee1 homolog, Wee1 like protein kinase, Wee1 tyrosine kinase, Wee1+ S. pombe, Wee1+ homolog |
| Swissprot | |
| Cellular Localization | Nucleus. |
| Concentration | 1.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.WEE1 (WEE1 G2 Checkpoint Kinase) is a Protein Coding gene. Among its related pathways are PLK1 signaling events and Cell cycle Role of 14-3-3 proteins in cell cycle regulation. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is WEE2. |
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