WWOX Polyclonal Antibody

Uniprot : Q9NZC7
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-17623

      Synonyms:5330426P09Rik,9030416C10Rik,Aberrant WW domain-containing oxidoreductase,D16S432E,EC 1.1.1.-,EIEE28,FOR,FRA16D,Fragile site FRA16D oxidoreductase,Fragile site FRA16D Oxireductase,HHCMA56,MGC55975,PRO0128,Putative oxidoreductase,SCAR12,SDR41C1,Short chain dehydrogenase/reductase family 41C,member 1,WOX1,WW domain containing oxidoreductase,WW domain-containing oxidoreductase,WW domain-containing protein WWOX,wwox,WWOX,zgc:55975

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms 5330426P09Rik,9030416C10Rik,Aberrant WW domain-containing oxidoreductase,D16S432E,EC 1.1.1.-,EIEE28,FOR,FRA16D,Fragile site FRA16D oxidoreductase,Fragile site FRA16D Oxireductase,HHCMA56,MGC55975,PRO0128,Putative oxidoreductase,SCAR12,SDR41C1,Short chain dehydrogenase/reductase family 41C,member 1,WOX1,WW domain containing oxidoreductase,WW domain-containing oxidoreductase,WW domain-containing protein WWOX,wwox,WWOX,zgc:55975
      Swissprot Q9NZC7
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Synthetic peptide of human WWOX
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:500-2000, IHC 1:20-100, ELISA 1:2000-5000
      Concentration 0.4 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Nucleus. Mitochondrion. Golgi apparatus. Partially localizes to the mitochondria. Translocates to the nucleus upon genotoxic stress or TNF stimulation (By similarity). Translocates to the nucleus in response to TGFB1. Isoform 5 and isoform 6 may localize in the nucleus.
      Tissue specificity Widely expressed. Strongly expressed in testis, prostate, and ovary. Overexpressed in cancer cell lines. Isoform 5 and isoform 6 may only be expressed in tumor cell lines.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated witHuman, Mouseultiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. 

      Images

      Immunohistochemistry of paraffin-embedded Human colorectal cancer using WWOX Polyclonal Antibody at dilution of 1/20

      Western Blot analysis of Mouse brain tissue using WWOX Polyclonal Antibody at dilution of 1/200

      • Show all (0)
      • Reviews (0)
      • Q&A (0)
      ... Show All Show Less
      MSDS for ELISA

      Browsing History


        People Also Bought