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ZNF395 Polyclonal Antibody

Cat:E-AB-13288
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human
  • Applications: IHC
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Product Details
Verified Samples Verified Samples in IHC:Human ovarian cancer
Dilution

IHC 1:50-1:200

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Synthetic peptide of human ZNF395
Abbre ZNF395
Synonyms DKFZp434K1210;HD gene regulatory region binding protein 2;HD gene regulatory region-binding protein 2;HD-regulating factor 2;HDBP-2;HDBP2;HDRF-2;Huntington disease gene regulatory region-binding protein 2;Huntington's disease gene regulatory region binding protein 2;Papillomavirus regulatory factor 1;papillomavirus regulatory factor PRF 1;Papillomavirus-binding factor;PBF;PRF-1;PRF1;PTTG1IP;Si-1-8-14;Zinc finger protein 395;ZN395;znf395
Swissprot
Cellular Localization Cytoplasm. Nucleus. May shuttle between nucleus and cytoplasm.
Concentration 0.8 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Epigenetics and Nuclear Signaling; Microbiology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF395 (Zinc finger protein 395), also known as PBF (Papillomavirus-binding factor) and HDBP2 (Huntington disease gene regulatory region-binding protein 2), is a 513 amino acid protein that contains one C2H2-type zinc finger. ZNF395 binds to the 3’-CCGG-5’ sequence within the papillomavirus promoter adjacent to a RUNX1-binding motif. It has also been established that ZNF395 binds to a seven base pair region within the Huntington's disease (HD) gene promoter, an essential element for HD gene expression. ZNF395 is widely expressed and probably shuttles between the nucleus and cytoplasm.