14-3-3 epsilon Polyclonal Antibody (E-AB-15794)
For research use only.
| Verified Samples |
Verified Samples in WB: Human brain malignant glioma, Human laryngocarcinoma Verified Samples in IHC: Human colon cancer, Human lung cancer |
| Dilution | WB 1:1000-1:5000, IHC 1:100-1:300 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human YWHAE |
| Abbre | YWHAE |
| Synonyms | 14 3 3 E, 14 3 3 epsilon, 14 3 3E, 14-3-3 protein epsilon, 14-3-3E, 1433E, Epididymis luminal protein 2, FLJ45465, FLJ53559, HEL2, KCIP 1, KCIP1, MDCR, MDS, Mitochondrial import stimulation factor L subunit, Protein kinase C inhibitor protein1, Tyrosine 3 monooxygenase/t |
| Swissprot | |
| Calculated MW | 29 kDa |
| Cellular Localization | Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction, Stem Cells |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins.This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog.It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity.It has also been implicated in the pathogenesis of small cell lung cancer.Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. |
Other Clones
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Other Formats
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Unconjugated
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