AARS2 Polyclonal Antibody (E-AB-10116)
                        For research use only.
| Verified Samples | 
                                Verified Samples in WB: SP20 Verified Samples in IHC: Human lymphoma, Human brain  | 
        
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 | 
| Isotype | IgG | 
| Host | Rabbit | 
| Reactivity | Human, Mouse, Rat | 
| Applications | WB, IHC | 
| Clonality | Polyclonal | 
| Immunogen | Recombinant protein of human AARS2 | 
| Abbre | AARS2 | 
| Synonyms | AARS 2, AARS2, AARSL, AlaRS, Alanine tRNA ligase, Alanine tRNA ligase 2 mitochondrial, Alanyl tRNA synthetase 2 mitochondrial, Alanyl tRNA synthetase like, COXPD8, Gm89, KIAA1270, LKENP, MGC69820, MT ALARS, MTALARS, Probable alanyl tRNA synthetase mitochondri, bA444E17.1 | 
| Swissprot | |
| Calculated MW | 107 kDa | 
| Cellular Localization | Mitochondrion matrix. | 
| Concentration | 0.4 mg/mL | 
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. | 
| Purification Method | Affinity purification | 
| Research Areas | Epigenetics and Nuclear Signaling | 
| Conjugation | Unconjugated | 
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. | 
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. | 
| background | The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain | 
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