AARS2 Polyclonal Antibody (E-AB-13885)
For research use only.
Verified Samples |
Verified Samples in WB: SP20 Verified Samples in IHC: Human thyroid cancer, Human liver cancer |
Dilution | WB 1:1000-1:5000, IHC 1:100-1:300 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Applications | WB, IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human AARS2 |
Abbre | AARS2 |
Synonyms | AARS 2, AARS2, AARSL, AlaRS, Alanine tRNA ligase, Alanine tRNA ligase 2 mitochondrial, Alanyl tRNA synthetase 2 mitochondrial, Alanyl tRNA synthetase like, COXPD8, Gm89, KIAA1270, LKENP, MGC69820, MT ALARS, MTALARS, Probable alanyl tRNA synthetase mitochondri, bA444E17.1 |
Swissprot | |
Calculated MW | 107 kDa |
Cellular Localization | Mitochondrion matrix. |
Concentration | 0.4 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain |
Other Clones
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Unconjugated
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