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For research use only.

Verified Samples Verified Samples in IHC: Human colorectal cancer
Dilution IHC 1:50-1:300
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human ABCB4
Abbre ABCB4
Synonyms ABC 21,  ABC B4,  ABC21,  ABCB 4,  ABCB4 protein,  ATP binding cassette sub family B MDR/TAP member 4,  ATP binding cassette sub family B member 4,  ATP-binding cassette sub-family B member 4,  Abcb4,  GBD1,  ICP3,  MDR 3,  MDR2,  MDR2/3,  MDR3,  MDR3 P glycoprotein,  MDR3 P gp,  Mul
Swissprot
Cellular Localization Cell membrane.
Concentration 2.04 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Antigen affinity purification
Research Areas Cancer,  Metabolism,  Signal transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.
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Unconjugated

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