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For research use only.

Verified Samples Verified Samples in IHC: Human liver cancer, Human prostate cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human ABI3BP
Abbre ABI3BP
Synonyms ABI gene family member 3 (NESH) binding protein,  ABI gene family member 3 binding protein,  ABI gene family member 3-binding protein,  ABI3BP,  FLJ41743,  FLJ41754,  Nesh BP,  Nesh binding protein,  Nesh-binding protein,  NeshBP,  Target of Nesh SH3,  Target of Nesh-SH3,  Tarsh
Swissprot
Cellular Localization Secreted.
Concentration 0.9 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background A target of NESH-SH3/Abi3bp (TARSH) was originally identified as an SH3 domain-binding molecule of the NESH-SH3/Abi3 protein that is involved in Rac-dependent actin polymerization. In recent studies, TARSH gene expression was dramatically induced in mouse embryonic fibroblasts (MEFs) replicative senescence and suppressed in human lung carcinoma specimens and thyroid carcinomas. However, the molecular mechanism underlying the regulation of TARSH in tumorigenesis remains unclear.
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Unconjugated

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