ADAR Polyclonal Antibody (E-AB-12696)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Human gastric cancer, Human lung cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ADAR |
| Abbre | ADAR |
| Synonyms | 136 kDa double-stranded RNA-binding protein, 136kDa double stranded RNA binding protein, ADAR, AGS6, AV2, Adar 1, Adar1, Adenosine deaminase RNA specific, Adenosine deaminase RNA specific 1, Adenosine deaminase acting on RNA 1 A, Adenosine deaminase that act on RNA |
| Swissprot | |
| Cellular Localization | Cytoplasm. Nucleus>nucleolus. Isoform 1 is found predominantly in cytoplasm but appears to shuttle between the cytoplasm and nucleus. Isoform 5 is found exclusively in the nucleolus. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Microbiology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. |
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