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For research use only.

Verified Samples Verified Samples in IHC: Human gastric cancer, Human brain
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human BAI1
Abbre ADGRB1
Synonyms B830018M07Rik,  BAI 1,  BAI1,  Brain specific angiogenesis inhibitor 1,  Brain-specific angiogenesis inhibitor 1,  GDAIF,  KIAA4089,  R75078,  mKIAA4089
Swissprot
Cellular Localization Cell membrane. Likely to be concentrated at cell-cell adhesion sites.
Concentration 0.5 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cardiovascular
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53.
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Unconjugated

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