AF/LE Purified Anti-Human CD32 Antibody[IV-3] (E-AB-F10750)
For research use only.
Conjugation: None (AF/LE)
APC Biotin Elab Fluor®488 Elab Fluor®647 Elab Fluor®700 Elab Fluor®Violet 450 FITC None (AF/LE) PE PE/Cyanine 5 PE/Cyanine 5.5 PE/Cyanine 7 PE/Elab Fluor®594 Unconjugated Show More
| Verified Samples | Verified Samples in FCM: Human peripheral blood granulocyte |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Isotype | Mouse IgG2b, κ |
| Host | Mouse |
| Reactivity | Human |
| Applications | FCM |
| Clonality | Monoclonal |
| Immunogen | Recombinant Human CD32 protein |
| Abbre | CD32 |
| Synonyms | FCG, CDw, Fcgr, IGFR, FCGR2B, CD32, CD32B, FCG2, FCGR2, IGFR2, CDw32, Fc-gamma-RIIb, FcRII-b, Low affinity immunoglobulin gamma Fc region receptor II-b, IgG Fc receptor II-b, Fc-gamma RII-b, CD32 antigen, Fc fragment of IgG, Fc gamma receptor IIB, Fc gamma RII, Fc gamma RIIB, FCG2B, Fc-gamma RII, FCRII, FcγRⅡ, IgG Fc receptor II beta, low affinity II, low affinity IIb, Low affinity immunoglobulin gamma Fc region receptor II, Ly-17, Lym 1, Lymphocyte antigen 17, receptor, receptor (CD32), receptor for, receptor for (CD32) |
| Swissprot | |
| Concentration | ≥ 1 mg/mL |
| Buffer | Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method. |
| Purification Method | >98%, Protein A/G purified |
| Research Areas | Immunology, Stem Cells |
| Clone No. | IV-3 |
| Conjugation | None (AF/LE) |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Shipping | Ice bag |
| background | CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform). |
| Cat.No. | Product Name | Clone No. |
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