AFDN Polyclonal Antibody (E-AB-15958)
For research use only.
| Verified Samples |
Verified Samples in IHC: Human colon cancer, Human lung cancer |
| Dilution | IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human MLLT4 |
| Abbre | AFDN |
| Synonyms | AF6, AFAD, ALL1-fused gene from chromosome 6 protein, Afadin, Mllt4, Protein AF6, Protein Af-6 |
| Swissprot | |
| Cellular Localization | Cell junction>adherens junction. Not found at cell-matrix AJs. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a multi-domain protein involved in signaling and organization of cell junctions during embryogenesis. It has also been identified as the fusion partner of acute lymphoblastic leukemia (ALL-1) gene, involved in acute myeloid leukemias with t(6;11)(q27;q23) translocation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, however, not all have been fully characterized. |
Other Clones
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Other Formats
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Unconjugated
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