AGRN Polyclonal Antibody (E-AB-15907)
For research use only.
Verified Samples |
Verified Samples in IHC: Human esophagus cancer, Human lung cancer |
Dilution | IHC 1:25-1:100 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | IHC |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human AGRN |
Abbre | AGRN |
Synonyms | AGRIN, AGRN, Agrin proteoglycan, FLJ45064, OTTHUMP00000044043 |
Swissprot | |
Cellular Localization | Secreted, extracellular space, extracellular matrix, Note: Synaptic basal lamina at the neuromuscular junction. |
Concentration | 0.3 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Neuroscience, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found. |
Other Clones
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Other Formats
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Unconjugated
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