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For research use only.

Verified Samples Verified Samples in IHC: Human esophagus cancer, Human lung cancer
Dilution IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human
Applications IHC
Clonality Polyclonal
Immunogen Synthetic peptide of human AGRN
Abbre AGRN
Synonyms AGRIN,  AGRN,  Agrin proteoglycan,  FLJ45064,  OTTHUMP00000044043
Swissprot
Cellular Localization Secreted, extracellular space, extracellular matrix, Note: Synaptic basal lamina at the neuromuscular junction.
Concentration 0.3 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Neuroscience,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes one of several proteins that are critical in the development of the neuromuscular junction (NMJ), as identified in mouse knock-out studies. The encoded protein contains several laminin G, Kazal type serine protease inhibitor, and epidermal growth factor domains. Additional post-translational modifications occur to add glycosaminoglycans and disulfide bonds. In one family with congenital myasthenic syndrome affecting limb-girdle muscles, a mutation in this gene was found.
Other Clones

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Unconjugated

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