AIM2 Polyclonal Antibody (E-AB-10974)

Citations ({{ citationsPage.numTotal }}) Manual MSDS

All	Size	Price	Qty
	200μL	$ 399.00
	120μL	$ 240.00
	60μL	$ 143.00
	20μL	$ 73.00

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Verified Samples	Verified Samples in IHC: Human thyroid cancer, Human lung cancer
Dilution	IHC 1:50-1:200
Isotype	IgG
Host	Rabbit
Reactivity	Human
Applications	IHC
Clonality	Polyclonal
Immunogen	Recombinant protein of human AIM2
Abbre	AIM2
Synonyms	AIM 2, AIM2, Absent in melanoma 2, Aim2, Interferon-inducible protein AIM2, OTTHUMP00000035296, PYHIN4
Swissprot	O14862
Cellular Localization	Nucleus.
Concentration	0.8 mg/mL
Buffer	Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method	Affinity purification
Research Areas	Cancer, Epigenetics and Nuclear Signaling
Conjugation	Unconjugated
Storage	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping	The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background	Interferon-inducible protein AIM2 (Absent in melanoma 2) is a 343 amino acid protein belonging to the HIN-200 family.Induced by IFN- , AIM2 is thought to act as a tumor suppressor by repressing NF B transcriptional activity.Localized to the nucleus, AIM2 contains one DAPIN domain and one HIN-200 domain.The DAPIN domain is composed mostly of -helixes and is a protein-protein interaction domain capable of binding other DAPIN domains.The HIN-200 domain has been shown to bind directly to DNA, which, along with the binding of another protein ASC, results in the activation of Caspase-1.

Cat.No.	Product Name	Sizes
E-AB-1003	Goat Anti-Rabbit IgG(H+L)(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1043	Streptavidin(peroxidase/HRP conjugated)	500μL , 120μL , 60μL
E-AB-1194	HRP-Goat Anti-Rabbit IgG(H+L) preadsorbed	500μL , 120μL , 1mL
E-IR-R217	2-step plus Poly-HRP Anti Mouse/Rabbit IgG Detection System (with DAB solution)	50mL , 18mL , 6mL , 3mL
E-IR-R220	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH9.0)	10mL , 3mL
E-IR-R221	Super Plus™ Highly Sensitive and Rapid Immunohistochemical Kit (pH6.0)	10mL , 3mL
E-IR-R304A	Western Blot Detection Kit	50Assays
E-IR-R304B	High Accuracy and Absorbability Western Blot Detection Kit	50Assays

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Unconjugated