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For research use only.

Verified Samples Verified Samples in WB: Human placenta, A549, Mouse brain, HepG2, Raji, Human fetal liver, Hela
Verified Samples in IHC: Human thyroid cancer, Human breast cancer
Dilution WB 1:500-1:2000,  IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse,  Rat
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human AK2
Abbre AK2
Synonyms mitochondrial,  ADK2,  AK 2,  ATP AMP transphosphorylase,  ATP-AMP transphosphorylase 2,  Adenylate kinase 2,  Adenylate kinase isoenzyme 2,  EC 2.7.4.3,  KAD2,  adenylate kinase 2,  ak2,  mitochondrial
Swissprot
Calculated MW 26 kDa
Cellular Localization Mitochondrion intermembrane space.
Concentration 0.2 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cancer,  Cell Biology,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.
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Unconjugated

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