AKR1C1 Polyclonal Antibody (E-AB-12710)
For research use only.
| Verified Samples |
Verified Samples in WB: Human liver cancer, Human breast infiltrive duct, Human fetal brain Verified Samples in IHC: Human colon cancer, Human ovarian cancer |
| Dilution | WB 1:500-1:2000, IHC 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human AKR1C1 |
| Abbre | AKR1C1 |
| Synonyms | 2-dihydrobenzene-1, 2-diol dehydrogenase, 20 ALPHA HSD, 20 alpha (3 alpha) hydroxysteroid dehydrogenase, 20 alpha hydroxysteroid dehydrogenase, 20-alpha-HSD, 20-alpha-hydroxysteroid dehydrogenase, 20ALPHAHSD, 2ALPHAHSD, AK1C1, AKR1C1, Aldo keto reductase famil |
| Swissprot | |
| Calculated MW | 37 kDa |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Metabolism, Developmental Biology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins.These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors.The enzymes display overlapping but distinct substrate specificity.This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone.This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. |
Other Clones
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Other Formats
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Unconjugated
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