AMACR Polyclonal Antibody (E-AB-10127)

For research use only.
Verified Samples |
Verified Samples in WB: A549, Jurkat Verified Samples in IHC: Human thyroid cancer |
Dilution | WB 1:500-1:2000, IHC 1:25-1:100 |
Isotype | IgG |
Host | Rabbit |
Reactivity | Human |
Applications | WB, IHC |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human AMACR |
Abbre | AMACR |
Synonyms | 2 methylacyl CoA racemase, 2-methylacyl-CoA racemase, AMACR, AMACRD, Alpha methylacyl CoA racemase, Alpha-methylacyl-CoA racemase, Amacr, CBAS4, EC 5.1.99.4, Macr1, RACE, RM |
Swissprot | |
Calculated MW | 42 kDa |
Cellular Localization | Peroxisome. Mitochondrion. |
Concentration | 0.1 mg/mL |
Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
Purification Method | Affinity purification |
Research Areas | Cell Biology, Metabolism, Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
background | This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. |
Other Clones
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Other Formats
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Unconjugated
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