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For research use only.

Verified Samples Verified Samples in WB: A549, Jurkat
Verified Samples in IHC: Human thyroid cancer
Dilution WB 1:500-1:2000,  IHC 1:25-1:100
Isotype IgG
Host Rabbit
Reactivity Human
Applications WB,  IHC
Clonality Polyclonal
Immunogen Recombinant protein of human AMACR
Abbre AMACR
Synonyms 2 methylacyl CoA racemase,  2-methylacyl-CoA racemase,  AMACR,  AMACRD,  Alpha methylacyl CoA racemase,  Alpha-methylacyl-CoA racemase,  Amacr,  CBAS4,  EC 5.1.99.4,  Macr1,  RACE,  RM
Swissprot
Calculated MW 42 kDa
Cellular Localization Peroxisome. Mitochondrion.
Concentration 0.1 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cell Biology,  Metabolism,  Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
Other Clones

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Unconjugated

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