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For research use only.

Verified Samples Verified Samples in IHC: Human colon cancer, Human lung cancer
Dilution IHC 1:50-1:200
Isotype IgG
Host Rabbit
Reactivity Human,  Mouse
Applications IHC
Clonality Polyclonal
Immunogen Recombinant protein of human ANAPC10
Abbre ANAPC10
Synonyms ANAPC 10,  APC10,  Anaphase promoting complex 10,  Anaphase promoting complex subunit 10,  Anaphase-promoting complex subunit 10,  Apc 10,  Cyclosome subunit 10,  DKFZP564L0562,  Doc 1,  Doc1,  OTTHUMP00000220297,  OTTHUMP00000220298,  S. cerevisiae,  anapc10,  homolog of
Swissprot
Cellular Localization Cytosol, Nucleus, anaphase-promoting complex, nucleoplasm.
Concentration 0.3 mg/mL
Buffer Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Purification Method Affinity purification
Research Areas Cell Biology
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
background ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940)
Other Clones

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Unconjugated

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