Anti-MERS-CoV Nucleocapsid Monoclonal Antibody (E-AB-V1281)
For research use only.
| Verified Samples |
Verified Samples in WB: Recombinant MERS-CoV Nucleoprotein / NP protein (His Tag) |
| Dilution | WB 1:1000-1:5000 |
| Isotype | IgG1 |
| Host | Mouse |
| Reactivity | MERS-CoV |
| Applications | WB, ELISA |
| Clonality | Monoclonal |
| Immunogen | Recombinant MERS-CoV Nucleoprotein / NP protein (His Tag) |
| Synonyms | NP, Nucleocapsid, Nucleoprotein, coronavirus NP, coronavirus Nucleocapsid, coronavirus Nucleoprotein, cov np, ncov NP, novel coronavirus Nucleoprotein |
| Concentration | 1 mg/mL |
| Buffer | 0.2 μm filtered solution in PBS. |
| Purification Method | Protein A Affinity |
| Clone No. | 10 |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
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