AP2A1 Polyclonal Antibody (E-AB-17662)
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For research use only.
| Verified Samples |
Verified Samples in WB: A431, 231, NIH/3T3 Verified Samples in IHC: Human liver cancer |
| Dilution | WB 1:500-2000, IHC 1:25-100 |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human AP2A1 |
| Abbre | AP2A1 |
| Synonyms | 100 kDa coated vesicle protein A, Ad, Adapter-related protein complex 2 alpha-1 subunit, adapter-related protein complex 2 subunit alpha-1, Adaptin alpha, Adaptin alpha A, Adaptor protein complex AP 2 alpha 1 subunit, adaptor protein complex AP 2 subunit alpha 1, Adaptor protein complex AP-2 subunit alpha-1, Adaptor protein complex AP2 alpha 1 subunit, adaptor protein complex AP2 subunit alpha 1, Adaptor related protein complex 2 alpha 1 subunit, Adaptor related protein complex AP 2 alpha 1 subunit, Adaptor related protein complex AP2 alpha 1 subunit, ADTAA, alpha 1, Alpha A adaptin, Alpha adaptin A, Alpha-adaptin A, alpha1 adaptin, Alpha1-adaptin, AP 2 alpha, AP 2 complex subunit alpha 1, AP-2 complex subunit alpha-1, AP2 complex subunit alpha 1, AP2-ALPHA, Ap2a1, CLAPA 1, CLAPA1, Clathrin adaptor complex AP2. alpha subunit, Clathrin assembly protein complex 2 alpha A large chain, Clathrin assembly protein complex 2 alpha-A large chain, Clathrin associated / assembly / adaptor protein large alpha 1, clathrin associated assembly adaptor protein large alpha 1, clathrin associated/assembly/adaptor protein, large, Plasma membrane adaptor HA 2/AP 2 adaptin alpha A subunit, Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit抗体 |
| Swissprot | |
| Calculated MW | 108 kDa |
| Cellular Localization | Cell membrane |
| Tissue Specificity | Expressed in the brain (at protein level) (PubMed:23676497). Isoform A: Expressed in forebrain, skeletal muscle, spinal cord, cerebellum, salivary gland, heart and colon. Isoform B: Widely expressed in tissues and also in breast cancer and in prostate carcinoma cells. |
| Concentration | 0.60 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20℃ Valid for 12 months. Avoid freeze/thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. |
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