APC Anti-Human CD183/CXCR3 Antibody[G025H7] (E-AB-F1156E)

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Cell Markers

Size	Price	Qty
100Tests	$ 312.00	- +
20Tests	$ 105.00	- +
100Tests×2	$ 468.00	- +

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Conjugation: APC

Isotype	Mouse IgG1, κ
Host	Mouse
Reactivity	Human
Applications	FCM
Clonality	Monoclonal
Isotype Control	APC Mouse IgG1, κ Isotype Control[MOPC-21]
Abbre	CD183/CXCR3
Synonyms	CKR-L2, CXC-R3, CXCR-3, CXCR3, GPR9
Swissprot	P49682
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Cell Biology, Immunology, Neuroinflammation, Neuroscience
Clone No.	G025H7
Conjugation	APC
Conjugation Information	APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Spectrum
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	Human CXCR3, also known as GPR9, is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11. It is a 38 kD seven-pass transmembrane receptor coupled to G-protein. CXCR3 is highly expressed by T cells (Th1), natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells. CXCR3 is important for effector lymphocyte recruitment into inflamed tissue in various inflammatory and autoimmune diseases, such as chronically inflamed liver, Crohn's disease, rheumatoid arthritis, multiple sclerosis, and inflammatory skin diseases.