APC Anti-Mouse CD163 Antibody[S15049F] (E-AB-F1295E)

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Size	Price	Qty
100Tests	$ 145.00	- +
50Tests	$ 85.00	- +
100Tests×2	$ 220.00	- +

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For research use only. Order now, ship in 3 days

Isotype	Rat IgG2a, κ
Host	Rat
Reactivity	Mouse
Applications	FCM
Clonality	Monoclonal
Abbre	CD163
Synonyms	MM130SCARI1, M130
Swissprot	Q2VLH6
Cellular Localization	Membrane;Secreted
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Immunology
Clone No.	S15049F
Conjugation	APC
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.