APC Anti-Mouse CD45R/B220 Antibody[RA3.3A 1/6.1] (E-AB-F1112UE)
For research use only.
Alternate Names | B220 |
Clone No | |
Leadtime | Order now, ship in 3 days |
Background | CD45R, also known as B220, is an isoform of CD45. It is a member of the protein tyrosine phosphatase (PTP) family with a molecular weight of approximately 180-240 kD. CD45R is expressed on B cells (at all developmental stages from pro-B cells through mature B cells), activated B cells, and subsets of T and NK cells. CD45R (B220) is also expressed on a subset of abnormal T cells involved in the pathogenesis of systemic autoimmunity in MRL-Fas<sup>lpr</sup> and MRL-Fas<sup>gld</sup> mice. It plays a critical role in TCR and BCR signaling. The primary ligands for CD45 are galectin-1, CD2, CD3, and CD4. CD45R is commonly used as a pan-B cell marker; however, CD19 may be more appropriate for B cell specificity. |
Abbre | CD45R;B220 |
Host | Rat |
Reactivity | Mouse |
Clonality | Monoclonal |
Isotype | Rat IgM, κ |
Isotype Control | E-AB-F09773E |
Applications |
FCM
|
Research Areas | Cell Biology;Immunology;Inhibitory Molecules;Neuroscience;Neuroscience Cell Markers |
Cellular Localization |
Membrane
|
Form | Liquid |
Concentration |
0.2 mg/mL
|
Conjugation | APC |
Conjugation Information | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
Spectrum | |
Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
Expiration Date | 12 months |
Shipping | Ice bag |
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APC
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FITC
PE
PE/Cyanine 5
PE/Cyanine 5.5
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PerCP
PerCP/Cyanine 5.5
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