APC Anti-Mouse MERTK Antibody[2B10C42] (AN00871E)
| Isotype | Rat IgG2a, κ |
| Host | Rat |
| Reactivity | Mouse |
| Applications | FCM |
| Clonality | Monoclonal |
| Isotype Control | APC Rat IgG2a, κ Isotype Control[2A3] |
| Abbre | MERTK |
| Synonyms | Mer, Eyk, Nyk, nmf12 |
| Swissprot | |
| Cellular Localization | Membrane |
| Concentration | 5 μL/Test |
| Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer. |
| Clone No. | 2B10C42 |
| Conjugation | APC |
| Conjugation Information | APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter). |
| Spectrum |
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| Storage | This product can be stored at 2-8°C for 24 months. Please protected from prolonged exposure to light and do not freeze. |
| Shipping | Ice bag |
| background | MerTK (Mer) is a member of the TAM (TYRO3/AXL/MerTK) family. It is a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. MerTK is mainly expressed by macrophages, monocytes, and dendritic cells. Its ligands are LGALS3, TUB, TULP1, and GAS6. MerTK is involved in the regulation of TLR signaling, efferocytosis, phagocytosis, cell survival, macrophage migration, and the inhibition of inflammation. |
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